Nature Medical Estrogen Steroids Estradiol Benzoate Hormonal Contraception
Estradiol Benzoate CAS:50-50-0
Appearance:white to light crystalline powder
Categories:Pharmaceutical Intermediates; Amino Acids; Intermediates & Fine Chemicals; Metabolites & Impurities; Pharmaceuticals; Steroids
Melting point: 191-198
Boiling point: 531.2 C at 760 mmHg
Refractive index: 1.604
Flash point: 212 C
Vapour Pressure: 4.08E-12mmHg at 25 C
Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position and is often used in combination with a progestin to induce estrus in domestic livestock. This compound binds to the human and murine estrogen receptor (ER ), and chicken ER with IC50 values in the range of 22-28 nM. This reflects a 6-10 fold reduction in binding affinity compared to estradiol.
Pharmaceutical material,Pregnant hormonal drugs.Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the tr eatment of lesions produced by diminution of bodily production of estrogens.